Estadio: Saluki Stadium Round: 1
Home Manager: Nick Hill Away Manager: Dave Steckel
| NCAAF | 2018/10/27 19:00 | Missouri St v SO Illinois | L | 35-49 |
| NCAAF | 2017/11/04 18:00 | SO Illinois v Missouri St | W | 28-36 |
| NCAAF | 2019/11/02 19:00 | South Dakota State v Missouri St | L | 35-14 |
| NCAAF | 2019/10/26 19:00 | Northern Iowa Panthers v Missouri St | L | 29-6 |
| NCAAF | 2019/10/19 19:30 | Missouri St v North Dakota State | L | 0-22 |
| NCAAF | 2019/10/12 19:00 | South Dakota v Missouri St | L | 45-10 |
| NCAAF | 2019/10/05 20:00 | Missouri St v Western Illinois | W | 37-31 |
| NCAAF | 2019/09/21 19:00 | Kennesaw State v Missouri St | L | 35-24 |
| NCAAF | 2019/09/15 00:00 | Missouri St v Tulane | L | 6-58 |
| NCAAF | 2019/08/30 01:00 | Missouri St v Northern Arizona | L | 23-37 |
| NCAAF | 2019/11/02 17:00 | SO Illinois v Indiana State | W | 23-14 |
| NCAAF | 2019/10/26 21:00 | SO Illinois v South Dakota | W | 48-28 |
| NCAAF | 2019/10/19 19:00 | Youngstown State v SO Illinois | W | 10-35 |
| NCAAF | 2019/10/12 23:00 | Illinois State v SO Illinois | L | 21-7 |
| NCAAF | 2019/10/05 19:00 | SO Illinois v South Dakota State | L | 10-28 |
| NCAAF | 2019/09/21 23:00 | SO Illinois v Arkansas State | L | 28-41 |
| NCAAF | 2019/09/14 23:00 | Tennessee Martin v SO Illinois | W | 14-28 |
| NCAAF | 2019/09/07 19:30 | SO Illinois v Massachusetts | W | 45-20 |