[17] Club América 3-0 Toluca [9] 2022-03-20 23:00
Estadio: Estadio Azteca Round: 11
Árbitro: Oscar Mejia Garcia Home Manager: Santiago Solari Away Manager: Ignacio Ambriz
Head to Head
| México - Liga MX | 2021/09/19 00:00 | Toluca v Club América | L | 3-1 |
| México - Liga MX | 2021/04/25 22:30 | Toluca v Club América | L | 3-1 |
| México - Liga MX | 2020/09/13 02:00 | Club América v Toluca | D | 1-1 |
| Europa - Partidos amistosos | 2020/07/04 02:00 | Club América v Toluca | W | 2-0 |
| México - Liga MX | 2019/08/11 17:00 | Toluca v Club América | W | 0-1 |
| México - Liga MX | 2019/04/21 17:00 | Toluca v Club América | L | 3-2 |
| México - Liga MX | 2018/12/03 00:30 | Club América v Toluca | W | 3-2 |
| México - Liga MX | 2018/11/30 01:00 | Toluca v Club América | D | 2-2 |
Home History
| México - Liga MX | 2022/03/13 03:00 | Chivas de Guadalajara v Club América | D | 0-0 |
| México - Liga MX | 2022/03/06 01:06 | Monterrey v Club América | L | 2-1 |
| México - Liga MX | 2022/03/02 03:00 | Club América v Querétaro | D | 1-1 |
| México - Liga MX | 2022/02/27 03:00 | Pumas de la UNAM v Club América | D | 0-0 |
| México - Liga MX | 2022/02/20 22:00 | Club América v Pachuca | L | 1-3 |
| México - Liga MX | 2022/02/17 01:00 | Mazatlán F.C. v Club América | L | 2-1 |
| México - Liga MX | 2022/02/13 03:00 | Santos Laguna v Club América | W | 2-3 |
| México - Liga MX | 2022/02/06 01:00 | Club América v Atlético San Luis | L | 2-3 |
Away History
| México - Liga MX | 2022/03/13 18:00 | Toluca v Pachuca | L | 0-3 |
| México - Liga MX | 2022/03/05 01:00 | Necaxa v Toluca | W | 0-1 |
| México - Liga MX | 2022/03/02 01:00 | Toluca v Tijuana | L | 1-2 |
| México - Liga MX | 2022/02/25 03:05 | Querétaro v Toluca | D | 1-1 |
| México - Liga MX | 2022/02/21 00:00 | Toluca v Cruz Azul | L | 1-4 |
| México - Liga MX | 2022/02/12 23:00 | Atlético San Luis v Toluca | W | 0-1 |
| México - Liga MX | 2022/01/22 03:00 | Mazatlán F.C. v Toluca | W | 1-2 |
| México - Liga MX | 2022/01/16 18:00 | Toluca v Santos Laguna | W | 3-1 |
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