Estadio: Arnold D. Stambaugh Stadium Round: 1
Home Manager: Doug Phillips Away Manager: Bob Nielson
| NCAAF | 2021/03/20 16:00 | South Dakota v Youngstown State | L | 10-28 |
| NCAAF | 2019/11/09 20:00 | Youngstown State v South Dakota | W | 21-56 |
| NCAAF | 2018/10/20 22:00 | Youngstown State v South Dakota | L | 29-17 |
| NCAAF | 2017/10/07 19:00 | South Dakota v Youngstown State | W | 31-28 |
| NCAAF | 2022/10/22 19:00 | SO Illinois v South Dakota | W | 24-27 |
| NCAAF | 2022/10/15 19:00 | South Dakota v Illinois State | L | 10-12 |
| NCAAF | 2022/10/08 19:00 | South Dakota v South Dakota State | L | 3-28 |
| NCAAF | 2022/09/24 18:00 | North Dakota State v South Dakota | L | 34-17 |
| NCAAF | 2022/09/17 18:00 | Cal Poly v South Dakota | W | 21-38 |
| NCAAF | 2022/09/10 19:30 | South Dakota v Montana | L | 7-24 |
| NCAAF | 2022/09/03 23:00 | South Dakota v Kansas State | L | 0-34 |
| NCAAF | 2021/11/27 23:00 | SO Illinois v South Dakota | L | 22-10 |
| NCAAF | 2022/10/22 20:00 | Youngstown State v Western Illinois | W | 28-27 |
| NCAAF | 2022/10/15 18:00 | Indiana State v Youngstown State | W | 42-48 |
| NCAAF | 2022/10/08 22:00 | North Dakota v Youngstown State | L | 35-30 |
| NCAAF | 2022/10/01 18:00 | Youngstown State v North Dakota State | L | 14-27 |
| NCAAF | 2022/09/17 16:00 | Youngstown State v Kentucky | L | 0-31 |
| NCAAF | 2022/09/10 18:00 | Dayton v Youngstown State | W | 16-49 |
| NCAAF | 2022/09/03 18:00 | Duquesne v Youngstown State | W | 14-31 |
| NCAAF | 2021/11/20 18:00 | Youngstown State v SO Illinois | W | 35-18 |