[12] Cruz Azul 0-2 Mazatlán F.C. [13] 2021-07-27 01:00
Estadio: Estadio Azteca Round: 1
Árbitro: Diego Montano Robles Home Manager: Juan Maximo Reynoso Away Manager: Benat San Jose
Head to Head
| México - Liga MX | 2021/03/04 03:00 | Cruz Azul v Mazatlán F.C. | W | 1-0 |
| México - Liga MX | 2020/09/19 02:30 | Mazatlán F.C. v Cruz Azul | W | 2-3 |
| México - Liga MX | 2016/01/10 02:30 | Mazatlán F.C. v Cruz Azul | D | 2-2 |
| México - Liga MX | 2015/07/25 22:00 | Cruz Azul v Mazatlán F.C. | L | 0-3 |
| México - Liga MX | 2015/04/18 00:30 | Mazatlán F.C. v Cruz Azul | L | 2-0 |
| México - Liga MX | 2014/10/25 22:00 | Cruz Azul v Mazatlán F.C. | W | 3-1 |
Home History
| México - Campeón de Campeones | 2021/07/18 23:30 | León v Cruz Azul | W | 1-2 |
| México - Liga MX | 2021/05/31 01:15 | Cruz Azul v Santos Laguna | D | 1-1 |
| México - Liga MX | 2021/05/28 02:00 | Santos Laguna v Cruz Azul | W | 0-1 |
| México - Liga MX | 2021/05/23 01:00 | Cruz Azul v Pachuca | W | 1-0 |
| México - Liga MX | 2021/05/20 01:30 | Pachuca v Cruz Azul | D | 0-0 |
| México - Liga MX | 2021/05/16 01:05 | Cruz Azul v Toluca | W | 3-1 |
| México - Liga MX | 2021/05/13 00:00 | Toluca v Cruz Azul | L | 2-1 |
| CONCACAF - Copa de Campeones | 2021/05/05 02:15 | Cruz Azul v Toronto FC | W | 1-0 |
Away History
| México - Liga MX | 2021/05/02 02:06 | Monterrey v Mazatlán F.C. | L | 1-0 |
| México - Liga MX | 2021/04/24 02:35 | Mazatlán F.C. v León | W | 4-3 |
| México - Liga MX | 2021/04/17 02:30 | Mazatlán F.C. v Atlas | D | 0-0 |
| México - Liga MX | 2021/04/12 02:06 | Tijuana v Mazatlán F.C. | W | 2-3 |
| México - Liga MX | 2021/04/03 01:30 | Puebla v Mazatlán F.C. | L | 3-1 |
| México - Liga MX | 2021/03/20 03:00 | Mazatlán F.C. v Club América | L | 0-1 |
| México - Liga MX | 2021/03/14 01:00 | Tigres UANL v Mazatlán F.C. | W | 1-2 |
| México - Liga MX | 2021/03/07 03:00 | Mazatlán F.C. v Chivas de Guadalajara | D | 1-1 |
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