[10] Boston River 2-1 Peñarol [8] 2022-10-12 22:00
Estadio: Estadio Parque Alfredo Víctor Viera Round: 13
Árbitro: Leodan Frankin Gonzalez Cabrera Home Manager: Ignacio Ithurralde Away Manager: Leonardo Ramos
Head to Head
| Copa de Uruguay | 2022/09/28 23:30 | Peñarol v Boston River | L | 4-3 |
| Uruguay - Torneo Apertura | 2022/05/21 22:30 | Peñarol v Boston River | L | 1-0 |
| Uruguay - Torneo Clausura | 2021/09/26 18:30 | Boston River v Peñarol | L | 2-5 |
| Uruguay - Torneo Apertura | 2021/05/30 21:00 | Peñarol v Boston River | L | 5-2 |
| Uruguay - Torneo Clausura | 2021/02/07 00:45 | Boston River v Peñarol | L | 1-2 |
| Uruguay - Torneo Intermedio | 2020/11/22 22:30 | Peñarol v Boston River | L | 2-0 |
| Uruguay - Torneo Apertura | 2020/08/16 20:30 | Peñarol v Boston River | L | 2-0 |
| Uruguay - Torneo Clausura | 2019/10/20 21:00 | Peñarol v Boston River | L | 1-0 |
Home History
| Uruguay - Torneo Clausura | 2022/10/09 19:00 | Liverpool Montevideo v Boston River | L | 3-2 |
| Uruguay - Torneo Clausura | 2022/10/02 19:00 | Boston River v Rentistas | W | 3-0 |
| Copa de Uruguay | 2022/09/28 23:30 | Peñarol v Boston River | L | 4-3 |
| Uruguay - Torneo Clausura | 2022/09/23 22:00 | Deportivo Maldonado v Boston River | L | 2-1 |
| Uruguay - Torneo Clausura | 2022/09/19 20:00 | Boston River v Danubio | L | 0-1 |
| Uruguay - Torneo Clausura | 2022/09/14 23:00 | Nacional De Football v Boston River | L | 1-0 |
| Uruguay - Torneo Clausura | 2022/09/10 18:00 | Boston River v Albion FC | W | 1-0 |
| Copa de Uruguay | 2022/09/07 23:00 | CA Central San Jose v Boston River | W | 0-2 |
Away History
| Uruguay - Torneo Clausura | 2022/10/09 22:30 | Peñarol v Plaza Colonia | L | 0-1 |
| Copa de Uruguay | 2022/10/05 23:30 | Plaza Colonia v Peñarol | W | 0-1 |
| Uruguay - Torneo Clausura | 2022/10/02 22:30 | Montevideo Wanderers v Peñarol | W | 0-2 |
| Copa de Uruguay | 2022/09/28 23:30 | Peñarol v Boston River | W | 4-3 |
| Uruguay - Torneo Clausura | 2022/09/24 22:00 | Peñarol v Torque | L | 0-1 |
| Uruguay - Torneo Clausura | 2022/09/18 22:00 | Peñarol v Cerrito | W | 3-1 |
| Uruguay - Torneo Clausura | 2022/09/15 18:30 | Liverpool Montevideo v Peñarol | W | 0-1 |
| Uruguay - Torneo Clausura | 2022/09/11 21:00 | Peñarol v Rentistas | D | 2-2 |
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