Estadio: Saluki Stadium Round: 1
Home Manager: Nick Hill Away Manager: Jared Elliot
| NCAAF | 2018/10/27 18:00 | Western Illinois v Northern Iowa Panthers | W | 37-17 |
| NCAAF | 2018/10/20 19:00 | Missouri St v Western Illinois | W | 14-31 |
| NCAAF | 2018/10/13 23:00 | North Dakota State v Western Illinois | L | 34-7 |
| NCAAF | 2018/10/06 19:00 | Western Illinois v Illinois State | L | 16-33 |
| NCAAF | 2018/09/29 20:00 | Youngstown State v Western Illinois | W | 38-45 |
| NCAAF | 2018/09/15 20:00 | Montana v Western Illinois | W | 27-31 |
| NCAAF | 2018/09/08 23:30 | Western Illinois v Illinois | L | 14-34 |
| NCAAF | 2018/08/31 01:00 | Western Illinois v Montana State | L | 23-26 |
| NCAAF | 2018/10/27 19:00 | Missouri St v SO Illinois | W | 35-49 |
| NCAAF | 2018/10/20 19:00 | SO Illinois v Indiana State | L | 21-24 |
| NCAAF | 2018/10/13 19:00 | SO Illinois v Illinois State | L | 3-51 |
| NCAAF | 2018/10/06 22:00 | SO Illinois v Youngstown State | L | 14-17 |
| NCAAF | 2018/09/29 23:00 | South Dakota v SO Illinois | L | 31-24 |
| NCAAF | 2018/09/15 23:00 | SE Missouri St v SO Illinois | L | 48-44 |
| NCAAF | 2018/09/08 20:00 | SO Illinois v Mississippi | L | 41-76 |
| NCAAF | 2018/08/30 23:00 | SO Illinois v Murray State Racers | W | 49-10 |