Estadio: Leavey Center Round: 1
Home Manager: Herb Sendek Away Manager: John Smith
| NCAAB | 2017/11/19 03:00 | Cal Poly San Luis Obispo v Santa Clara | W | 63-59 |
| NCAAB | 2014/12/23 22:00 | Santa Clara v Cal Poly San Luis Obispo | W | 58-69 |
| NCAAB | 2005/12/10 12:00 | Santa Clara v Cal Poly San Luis Obispo | L | 73-58 |
| NCAAB | 2004/12/12 12:00 | Cal Poly San Luis Obispo v Santa Clara | W | 98-89 |
| NCAAB | 2019/03/10 03:00 | UC Santa Barbara v Cal Poly San Luis Obispo | L | 92-82 |
| NCAAB | 2019/03/08 03:00 | UC Irvine v Cal Poly San Luis Obispo | L | 110-72 |
| NCAAB | 2019/03/03 03:00 | Cal Poly San Luis Obispo v Long Beach State | L | 85-94 |
| NCAAB | 2019/03/01 03:00 | Cal Poly San Luis Obispo v CS Fullerton | L | 75-86 |
| NCAAB | 2019/02/24 03:00 | Hawaii v Cal Poly San Luis Obispo | W | 80-88 |
| NCAAB | 2019/02/22 03:00 | Cal Poly San Luis Obispo v UC Irvine | L | 47-74 |
| NCAAB | 2019/02/15 05:00 | Cal Poly San Luis Obispo v Hawaii | L | 54-75 |
| NCAAB | 2019/02/10 03:00 | Long Beach State v Cal Poly San Luis Obispo | L | 76-68 |
| NCAAB | 2019/11/06 03:00 | UC Santa Cruz v Santa Clara | W | 52-97 |
| NCAAB | 2019/03/09 04:20 | San Diego v Santa Clara | L | 62-45 |
| NCAAB | 2019/03/03 03:00 | Santa Clara v Portland | W | 78-62 |
| NCAAB | 2019/03/01 04:00 | Santa Clara v Loyola Marymount | L | 70-72 |
| NCAAB | 2019/02/24 04:00 | San Francisco v Santa Clara | W | 65-68 |
| NCAAB | 2019/02/17 02:00 | Pacific v Santa Clara | W | 59-64 |
| NCAAB | 2019/02/15 04:00 | Saint Mary's CA v Santa Clara | L | 66-55 |
| NCAAB | 2019/02/10 04:00 | Santa Clara v San Francisco | L | 72-78 |